College of Pharmacy, Mustansiriyah University discussed a Ph.D. thesis on the efficacy and safety of vinorelbine-loaded vesicles as a targeted drug carrier for targeting cancer cells by the postgraduate student, Mr. Ali Nima Wanas.

The thesis aimed at enhancing the therapeutic efficacy and pharmacological safety of vinorelbine when administered intravenously as a targeted drug carrier for targeting cancer cells, particularly lung and breast cancer due to the presence of active receptors that respond to hyaluronic acid and contribute to the incorporation of the acid to improve drug targeting efficiency.

The thesis included an in vitro (in vitro) and in vivo evaluation to compare the therapeutic and diagnostic performance of the activated carrier, the non-activated carrier and the commercial drug formulation.

The thesis confirmed that the hyaluronic acid-activated nanocarrier is a promising system for selectively delivering vinorelbine to tumors, opening new horizons in the field of targeted cancer therapy.

The thesis concluded by evaluating the efficacy and safety of the vinorelbine-loaded vesicle and proposing future improvements in formulation or preparation methods compared to other forms, reflecting a reduction in toxicity.