College of Science at Thi-Qar University discussed a Ph.D. thesis on the synthesis and study of the establishment of some new azetidine-2-one compounds as antioxidants and anticancer agents by the postgraduate student, Ms. Wafaa Mahdi Sajit.
The thesis aimed at designing and synthesizing
new azetidine-2-one organic compounds containing heterocyclic rings and studying
their potential biological effectiveness as antioxidants and anticancer agents,
as well as meeting the growing global need for effective and safe chemical
compounds in the treatment of cancer.
The thesis highlighted two parallel
approaches to synthesize the compounds: one conventional and the other
environmentally friendly, using microwave radiation, as well as improving
synthesis efficiency and reducing harmful environmental impacts.
The thesis demonstrated that some of the
newly synthesized compounds exhibited promising antioxidant properties, as well
as potential anticancer activity, suggesting their potential as a basis for
developing future drugs within drug design programs.
The thesis concluded that introducing
heterogeneous rings into the molecular structures of organic compounds and
employing environmentally friendly synthesis techniques represents an effective
approach for developing highly effective and safe pharmaceutical compounds.
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